SwaLife Biotech is formed based on the five novel bioactive alkaloids discovered from plants. The focus is to do synthesis and semi synthesis of discovered compounds and look for activity in skin and breast cancer targeting the inhibition of proteins or enzyme involved in DNA damage response (DDR), hallmarks of cancer disease. Using our novel methodology, we have isolated alkaloids from plant material. Chemical characterisations have shown that the five isolated compounds identified so far are novel. In vitro experiments have shown their anti-cancerous activity in breast and skin cancer cells. A target-specific experiment showed that novel alkaloids have inhibited DDR in breast and skin cancer. As our product has activity against DNA damage repair pathway, it is more likely to prevent from emergence of drug resistance strain and provide no escape route for cancer survival.

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